ClinicaLister integrates 18+ databases spanning clinical trial registries, drug regulatory databases, device submission records, substance registries, safety reporting systems, publication repositories, commercial pricing data, and the Monarch Disease Ontology — synchronized throughout the day and cross-linked.
Comprehensive coverage of global clinical trial data
The world's largest clinical trial registry, covering interventional and observational studies across all therapeutic areas and geographies. Primary source for all clinical trial data.
The European Union Clinical Trials Information System, providing cross-references to EU trial numbers, status, phase, recruiting member states, and results availability. Only includes CTIS trials that are also registered in ClinicalTrials.gov.
Collapse every synonym, subtype, and vocabulary variant into one canonical disease — so a single search finds every relevant trial
Community-maintained disease ontology providing stable canonical disease identifiers, curated parent/subtype relationships, and Orphanet-derived rare-disease flags. Each trial condition is resolved to its canonical MONDO disease, giving the platform a structured disease dimension that unifies every vocabulary variant into a single queryable layer.
FDA and EMA drug approvals with patent and exclusivity intelligence
Comprehensive data on FDA-approved drug products including brand/generic names, approval dates, marketing status, sponsors, active ingredients, and regulatory designations
European Public Assessment Reports covering centrally authorized medicines with therapeutic area, authorization status, ATC codes, and marketing authorization holders
Therapeutic equivalence evaluations, patent listings with expiration dates, and marketing exclusivity periods for FDA-approved drugs
National Drug Code product listings with proprietary/nonproprietary names, dosage forms, routes, DEA schedules, labeler information, and marketing dates
Medical device submissions, classifications, and identifications
Premarket submissions covering 510(k), PMA, HDE, and DE NOVO pathways with applicant information, decision dates, device classification, and predicate device references
The Global Unique Device Identification Database providing device identifiers, brand names, MRI safety status, latex content, sterilization methods, and manufacturer details
Product code classifications with device class, medical specialty, review panel, regulation number, and GMP/implant/life-sustaining flags
Substance registries and adverse event reporting
The Global Substance Registration System providing UNII codes, preferred substance names, molecular formulas, molecular weight, CAS numbers, and substance class designations
Manufacturer and User Facility Device Experience reports providing adverse event narratives, patient demographics, severity outcomes, and remedial actions for medical devices
Device recall records with classification (Class I/II/III), recalling firm, reason for recall, distribution pattern, and initiation/termination dates
Research publications linked to clinical trials
MEDLINE-indexed biomedical literature linked to clinical trials through NCT number cross-referencing, providing evidence context and research citations
European life sciences literature repository with open-access full-text articles linked to trial records for comprehensive publication coverage
Drug pricing, shortage tracking, and payment transparency data
FDA-approved drug labeling including package inserts, medication guides, and prescribing information for comprehensive product intelligence
National Average Drug Acquisition Cost data providing retail pharmacy pricing intelligence for drug cost analysis and market comparison
Medicare Average Sales Price data for Part B drugs, enabling reimbursement and pricing trend analysis
Active FDA drug shortage tracking with supply status, estimated resolution dates, and therapeutic alternatives
Physician and teaching hospital payment data from pharmaceutical and device manufacturers for transparency intelligence
Medicare Part D prescription drug spending data with utilization metrics and cost trends
ClinicaLister doesn't just store data from these sources — it cross-links them to create a connected intelligence network:
Clinical trials are linked to FDA and EMA drug records. Only verified links are shown — each with a confidence indicator and full provenance.
FDA and EMA drugs are linked to GSRS substance records via UNII codes, providing molecular-level data for each active ingredient.
FDA drugs are enriched with Orange Book patent listings and exclusivity periods, enabling competitive timeline analysis.
FDA drugs are linked to their NDC product listings, showing packaging, labeling, DEA schedule, and marketing dates.
Clinical trials are linked to FDA device submissions. Verified links include a confidence indicator and full provenance.
FDA device submissions are cross-referenced with GUDID records via foreign key relationships, providing device identification, safety, and sterilization data.
FDA devices are enriched with product code classification data including device class, medical specialty, and regulatory definitions.
FDA devices are linked to MAUDE adverse event reports and recall records, providing safety signal data directly within the trial context.
US clinical trials (ClinicalTrials.gov) serve as the primary source, with CTIS records cross-referenced only when trials exist in both registries. This enables transatlantic trial tracking while maintaining ClinicalTrials.gov as the authoritative data source.
Clinical trials are linked to PubMed and Europe PMC publications through NCT number cross-referencing, providing research evidence context.
Every trial condition is resolved to one or more canonical MONDO diseases, so filtering for "Lung Cancer" automatically includes NSCLC, SCLC, adenocarcinoma, and every other subtype — with coverage continually expanding across the long tail.
Cross-links are the surface. Underneath, every record resolves to a canonical identity, so the connections are consistent, confidence-scored, and traceable.
Drugs collapse to UNII-anchored molecules (9,100+, 83% UNII-anchored), conditions to MONDO diseases, devices to GUDID — one identity per real-world thing.
Every link is scored High, Medium, or Low confidence. Verified links are shown by default; AI suggestions wait for validation, and each is curated before it appears.
Every link records where it came from and how it matched — and structural guardrails keep contaminated links (placebo, counterions, look-alike drugs) out.
ClinicaLister maintains high data coverage against source totals. Data quality is regularly monitored through automated audits comparing database record counts against each source's published totals.