Diseases & Knowledge Graph
Explore your portfolio by MONDO disease — cards, table, search and charts — plus the interactive disease ↔ molecule ↔ trial knowledge graph.
The Diseases tab
Every trial's free-text conditions are mapped to canonical MONDO ontology terms, so "colon cancer", "colorectal carcinoma" and similar collapse to one disease. The Diseases tab rolls your followed trials up by MONDO term so you can see — and filter by — the diseases your portfolio actually covers.
- Each disease shows its canonical name, MONDO id, how many of your followed trials map to it, whether it's a rare disease, and how the mapping was made.
- Switch between a Cards view and a Table view; search narrows the list as you type.
- A "Rare only" toggle focuses on rare diseases.
Filter your portfolio by disease
Click a disease (a card, a table row, or a bar in the Top Diseases chart) to filter the entire dashboard — table, map, and every other chart — to the trials mapped to that disease. It works exactly like clicking a drug or a phase: selections stack, and Clear Filters (or clicking the disease again) removes it.
MONDO disease charts
Three charts on the Dashboard summarize the disease layer (full calculations are in the Dashboard Charts guide):
| Chart | What it shows |
|---|---|
| MONDO Top Diseases | The most-covered diseases, with both your following count and the total trials linked database-wide. Click a bar to filter. |
| MONDO Rare vs Non-rare | How your distinct diseases split between rare and non-rare. |
| MONDO Disease Match Method | How condition→MONDO mappings were made — exact, alias, LLM, or inferred from trial text (a proxy for mapping confidence). |
Disease detail & ontology context
Open a disease to see where it sits in the ontology and what's studied for it:
- External references — deep links to OMIM, Orphanet, ICD-10, MeSH, DOID, EFO, NCIt and more for the term.
- Hierarchy — Parents, the full Ancestors path, and Children (narrower terms), so you can see broader/narrower diseases.
- Landscape — a ranked table of the molecules studied for the disease, with trial counts and phases; click a molecule to open its full drug details.
Knowledge Graph
Each disease detail offers an interactive graph view: the disease at the center, the molecules studied for it around it, and — on expand — the trials at each molecule × disease intersection (restricted to your followed trials). It's the same data as the landscape table, navigable as a node-link graph.
- Click a molecule to expand its trials; click a trial node's "View details" to open the trial, or a molecule's "Drug details" to open the drug modal.
- Fullscreen, pinch/drag to pan & zoom (desktop and mobile), and a "Move subtree" mode to drag a molecule together with its trials.
- Filter mode turns a click into a portfolio filter — narrow the dashboard to a molecule's or a single trial's trials.
- The inverse graph is available from any drug: the drug details modal has a Graph button showing drug → diseases → trials, with a "Disease details" jump back into the disease view.
Where disease data comes from
Conditions are mapped to the MONDO (Monarch Disease Ontology) via exact-name, alias, and LLM-assisted matching, stored as trial→condition links. The molecule and trial relationships in the landscape and graph come from the same molecule/disease links that power the drug intelligence, joined to the MONDO ontology (parents, ancestors, children, and the rare-disease flag).