Diseases & Knowledge Graph

The Diseases tab

Every trial's free-text conditions are mapped to canonical MONDO ontology terms, so "colon cancer", "colorectal carcinoma" and similar collapse to one disease. The Diseases tab rolls your followed trials up by MONDO term so you can see — and filter by — the diseases your portfolio actually covers.

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• Each disease shows its canonical name, MONDO id, how many of your followed trials map to it, whether it's a rare disease, and how the mapping was made — as Exact match, AI mapped or (weakest, in amber) AI inferred badges.
• Switch between Cards, Table, and By link views. By link lists one row per trial–disease link (NCT ID, Trial, Disease, MONDO ID, Match, Confidence, Rare).
• Search diseases… narrows the list as you type.
• A "Rare only" checkbox focuses on rare diseases.

Filter your portfolio by disease

Filters on the Diseases tab narrow the whole Follow-Up page — dashboard, Trials tab, map, and every other chart — to the trials mapped to the diseases that remain. Clear Filters resets them.

• Tick Rare only to keep just the trials mapped to a rare disease.
• In the Table or By link view, use the funnel icon in a column header (for example Disease, Rare or Match) to keep only the rows you tick.
• On the Dashboard, click a bar in MONDO Top Diseases, or a slice of MONDO Rare vs Non-rare Diseases, to filter the same way. Chart selections stack with your other filters.
• Clicking a disease card or table row opens that disease's detail panel rather than filtering.

MONDO disease charts

Three charts on the Dashboard summarize the disease layer (full calculations are in the Dashboard Charts guide):

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Disease detail & ontology context

Open a disease to see where it sits in the ontology and what's studied for it:

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• External references — deep links to OMIM, Orphanet, ICD-10, MeSH, DOID, EFO, NCIt and more for the term.
• Hierarchy — Parents, every Ancestor term, and Children (narrower terms), so you can see broader/narrower diseases.
• Landscape — a ranked table of the molecules studied for the disease, with trial counts and phases; click a molecule to open its full drug details.

Knowledge Graph

Each disease detail offers an interactive graph view: the disease at the center, the molecules studied for it around it, and — on expand — the trials at each molecule × disease intersection (restricted to your followed trials). It's the same data as the landscape table, navigable as a node-link graph.

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• By default the graph shows the molecules with the most trials and gathers the rest into a "+N more" node; the All N button shows every molecule, and Top 12 switches back.
• Click a molecule to expand its trials; click a trial node's "View details" to open the trial, or a molecule's "Drug details" to open the drug modal.
• Fullscreen, pinch/drag to pan & zoom (desktop and mobile), and a "Move subtree" mode to drag a molecule together with its trials.
• Filter mode turns a click into a portfolio filter — narrow the dashboard to a molecule's or a single trial's trials.
• The inverse graph is available from any drug: the drug details modal has a Graph button showing drug → diseases → trials, with a "Disease details" jump back into the disease view.

Where disease data comes from

Conditions are mapped to the MONDO (Monarch Disease Ontology) via exact-name, alias, and LLM-assisted matching, stored as trial→condition links. The molecule and trial relationships in the landscape and graph come from the same molecule/disease links that power the drug intelligence, joined to the MONDO ontology (parents, ancestors, children, and the rare-disease flag).